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About
With founders who are global leaders in the structural biology of 14-3-3 proteins and their role in a wide range of protein-protein interactions, our team is developing a new class of medicines that can modulate previously undruggable targets and influence currently accessible ones in new ways. These small molecule stabilizers of 14-3-3:client complexes have the potential to address serious unmet needs in important therapeutic areas including cancer, metabolic disorders, neurodegenerative and infectious diseases.
Our company is committed to aggressively expanding the boundaries of medicine through treatments that modulate some of the most challenging and potentially impactful targets identified across the proteome, with the goal of treating diseases that currently lack a cure and helping patients live longer and healthier lives.
![0022_Ambagon-Photo-MArkinEdit](https://www.ambagontx.com/wp-content/uploads/2021/12/0022_Ambagon-Photo-MArkinEdit.png)
Michelle Arkin, Ph.D.
Co-founder
![0021_Ambagon-Photo-ZZhang4898Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0021_Ambagon-Photo-ZZhang4898Edit.png)
Zhen Zhang, Ph.D.
Senior Director, Cell Biology
![0000_Ambagon-Photo-GMiley1509Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0000_Ambagon-Photo-GMiley1509Edit.png)
Galen Miley, Ph.D.
Senior Scientist, Biochemistry
![0005_Ambagon-Photo-LStevers1248Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0005_Ambagon-Photo-LStevers1248Edit.png)
Loes Stevers, Ph.D.
Principal Scientist, Biochemistry
![0003_Ambagon-Photo-LDemmers1406Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0003_Ambagon-Photo-LDemmers1406Edit.png)
Laura Demmers, Ph.D.
Senior Scientist, Proteomics
![0002_Ambagon-Photo-ESijbesma1294Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0002_Ambagon-Photo-ESijbesma1294Edit.png)
Eline Sijbesma, Ph.D.
Senior Scientist, Biochemistry
![Ambagon-Headshots-MichelleHowarth](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-MichelleHowarth.png)
Michelle Howarth, Ph.D.
Principal Scientist, Cell Biology
![0011_Ambagon-Photo-LBrunsveld1806Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0011_Ambagon-Photo-LBrunsveld1806Edit.png)
Luc Brunsveld, Ph.D.
Co-founder
![0013_Ambagon-Photo-RdeVries1648Edit](https://www.ambagontx.com/wp-content/uploads/2021/12/0013_Ambagon-Photo-RdeVries1648Edit.png)
Rens de Vries, Ph.D.
Principal Scientist, Structural Biology
![Ambagon-Headshots-DharaAmin](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-DharaAmin.png)
Dhara Amin, Ph.D.
Associate Director, Cell Biology
![Ambagon-Headshots-SamuelChang](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-SamuelChang.png)
Samuel Chung, Ph.D.
Senior Scientist, Cell Biology
![Ambagon-Headshots-PaulHollenbach](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-PaulHollenbach.png)
Paul Hollenbach
Scientist, Cell Biology
![Ambagon-Headshots-TaggraNicolleJackson](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-TaggraNicolleJackson.png)
Taggra-Nicole Jackson
Associate Scientist, Cell Biology
![Ambagon-Headshots-KarolinaKaminska](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-KarolinaKaminska.png)
Karolina Kaminska
Senior Research Associate, Cell Biology
![Ambagon-Headshots-MeredithKuo](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-MeredithKuo.png)
Meredith Kuo, Ph.D.
Principal Scientist, Cell Biology
![Ambagon-Headshots-JiaXie](https://www.ambagontx.com/wp-content/uploads/2022/12/Ambagon-Headshots-JiaXie.png)
Jia Xie, Ph.D.
Principal Scientist, Cell Biology
![MaartenAltelaar](https://www.ambagontx.com/wp-content/uploads/2022/12/MaartenAltelaar.png)
Maarten Altelaar, Ph.D.
Executive Director, Proteomics
![MrudulaSrikanth](https://www.ambagontx.com/wp-content/uploads/2022/12/MrudulaSrikanth.png)
Mrudula Srikanth
Senior Research Associate, Biochemistry
![TomvandeWijngaart](https://www.ambagontx.com/wp-content/uploads/2022/12/TomvandeWijngaart.png)
Tom van de Wijngaart
Associate Scientist, Structural Biology
![LauraButhker](https://www.ambagontx.com/wp-content/uploads/2022/12/LauraButhker.png)
Laura Büthker
Senior Research Associate, Biochemistry
![CeriZwart](https://www.ambagontx.com/wp-content/uploads/2022/12/CeriZwart.png)
Ceri Zwart
Associate Scientist, Proteomics
![Ambagon-Denise Reyes-Placeholder](https://www.ambagontx.com/wp-content/uploads/2023/10/Ambagon-Denise-Reyes-Placeholder.png)
Denise Reyes
Associate Scientist, Cell Biology
![Ambagon-David Elion-Placeholder](https://www.ambagontx.com/wp-content/uploads/2023/10/Ambagon-David-Elion-Placeholder.png)
David Elion, Ph.D.
Senior Scientist, Cell Biology
![Ambagon-Peipei Li-Placeholder](https://www.ambagontx.com/wp-content/uploads/2023/10/Ambagon-Peipei-Li-Placeholder.png)
Peipei Li, Ph.D.
Principal Scientist, Bioinformatics
![Ambagon-Vicky Lin-Placeholder](https://www.ambagontx.com/wp-content/uploads/2023/10/Ambagon-Vicky-Lin-Placeholder.png)
Vicky Lin, Ph.D.
Sr. Principal Scientist, Cell Biology
![Ambagon-Enes Aydin-Placeholder](https://www.ambagontx.com/wp-content/uploads/2023/10/Ambagon-Enes-Aydin-Placeholder.png)
Enes Aydin
Senior Research Associate, Cell Biology
![Ambagon-Donna Debets-Placeholder](https://www.ambagontx.com/wp-content/uploads/2023/10/Ambagon-Donna-Debets-Placeholder.png)
Donna Debets, Ph.D.
Senior Scientist, Proteomics
Investors
![RAcapital logo](https://www.ambagontx.com/wp-content/uploads/2021/11/logo-racapital.png)
![mrl ventures fund logo](https://www.ambagontx.com/wp-content/uploads/2021/11/logo-mrl.png)
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![inkef capital logo](https://www.ambagontx.com/wp-content/uploads/2021/11/logo-inkef.png)
![droia ventures logo](https://www.ambagontx.com/wp-content/uploads/2021/11/logo-droia.png)
![abbvie logo](https://www.ambagontx.com/wp-content/uploads/2021/11/logo-abbvie.png)